myeloma

myeloma
= multiple myeloma; = myelomatosis; n.
a malignant disease of the bone marrow, characterized by two or more of the following criteria:
1) the presence of an excess of abnormal malignant plasma cells in the bone marrow;
2) typical lytic deposits in the bones on X-ray, giving the appearance of holes;
3) the presence in the serum of an abnormal gammaglobulin, usually IgG (an immunoglobulin; see paraprotein). Bence-Jones protein may also be found in the serum or urine. The patient may complain of tiredness due to anaemia and of bone pain and may develop pathological fractures. Treatment is usually with such drugs as melphalan or cyclophosphamide, with local radiotherapy to particular areas of pain.
See also: plasmacytoma

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  • myeloma — myeloma. См. миелома. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • myeloma — (n.) 1857, from comb. form of Gk. myelos marrow + OMA (Cf. oma) …   Etymology dictionary

  • myeloma — [mī΄ə lō′mə] n. pl. myelomas or myelomata [mī΄ə lōmə tə] [ MYEL(O) + OMA] a malignant tumor of the bone marrow, consisting generally of abnormal plasma cells myelomatous [mī΄əläm′ə təs, mī΄əlō′mətəs] adj …   English World dictionary

  • myeloma — /muy euh loh meuh/, n., pl. myelomas, myelomata / meuh teuh/. Pathol. a tumor of plasma cells, arising in bone marrow, and often occurring at multiple sites, as in the vertebrae and flat skull bones. Cf. multiple myeloma. [1855 60; MYEL + OMA] *… …   Universalium

  • Myeloma — A tumor of antibody producing cells, called plasma cells, that are normally found in the bone marrow. * * * 1. A tumor composed of cells derived from hemopoietic tissues of the bone marrow. 2. A plasma cell tumor. [myelo + G. oma, tumor] Bence… …   Medical dictionary

  • Myeloma Canada — Type Non profit Founded 2004 Key people John F. Lemieux Co Founder and President Aldo E. Del Col Co Founder and Executive Director Website www.myelomacanada.ca Myeloma Canada …   Wikipedia

  • Myeloma protein — is usually a monoclonal antibody or immunoglobulin fragment that is produced by malignant myeloma cells, or plasma cells. Other terms for this protein is M protein, spike protein,or paraprotein. This proliferation of the myeloma protein has… …   Wikipedia

  • Myeloma Foundation — may refer to: Multiple Myeloma Research Foundation International Myeloma Foundation Africa Myeloma Foundation This disambiguation page lists articles associated with the same title. If an …   Wikipedia

  • myeloma cast nephropathy — myeloma kidney …   Medical dictionary

  • myeloma kidney — renal changes occurring in multiple myeloma, due to filtration of large amounts of Bence Jones protein; they include tubular atrophy with multinucleated giant cells in the tubule walls and interstitium, as well as formation of myeloma casts (see… …   Medical dictionary

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